NAD+ gets talked about a lot in longevity and biohacking circles, sometimes with more confidence than the science actually supports. We'd rather give you the real picture than a marketing one, especially since we offer it ourselves.

What NAD+ actually is

Nicotinamide adenine dinucleotide, NAD+, is a coenzyme present in every cell in your body. It's central to two things: converting food into usable cellular energy, and acting as a required cofactor for PARP enzymes, the proteins your cells rely on to repair damaged DNA. Neither of those facts is controversial, they're basic, well-established cell biology.

What's also well established is that NAD+ levels decline with age, by some estimates, roughly halving between young adulthood and middle age. This decline is real and measurable. What's genuinely still being studied is what, precisely, restoring those levels does for a healthy adult.

Where the evidence is solid, and where it isn't

Much of the strongest data on boosting NAD+ levels comes from animal studies, particularly mice, where researchers have shown measurable effects on cellular energy metabolism and markers of aging. Translating that directly to humans is where the evidence gets thinner. Large-scale, randomized human trials on NAD+ supplementation, especially via IV, are still limited.

The most robust human clinical evidence for IV NAD+ specifically exists in a fairly different context: supportive treatment during opioid and alcohol withdrawal, not general wellness or longevity. That's a real, documented use case, but it's not the same claim as "NAD+ IV therapy slows aging" or "restores youthful energy," claims you'll see in plenty of wellness marketing that outpace what's actually been demonstrated.

So why do we offer it?

Because the underlying mechanism is real, NAD+ genuinely is required for cellular energy production and DNA repair, and because it's an area of legitimate, active research that a meaningful number of our clients are specifically interested in exploring as part of a broader wellness routine. We think that's a reasonable thing to offer, as long as we're honest about what's proven versus what's still being studied.

What we won't do is tell you it will definitely make you feel a specific way, or that it's a substitute for sleep, training, nutrition, or actual medical care. If a clinic promises you certainty on this particular topic, that's worth being skeptical of, regardless of who's making the promise.

Want to explore it for yourself? Learn more about our NAD+ drip →

The honest summary: real biology, real decline with age, promising animal data, and human evidence that's still catching up. We'd rather tell you that plainly than oversell it.